Table 3.
Disposition of radioactivity 72 h following a single gavage administration of [14C]triclocarban in micea
| Sample | Collection Interval (h) | Percent of dose | |
|---|---|---|---|
| Male | Female | ||
| 50 mg/kg | 50 mg/kg | ||
| Urineb | 0 - 72 | 3.32 ± 1.56 | 4.69 ± 1.35 |
| Feces | 0 – 24 | 68.9 ± 10.5 | 67.5 ± 6.25 |
| 24 – 48 | 5.6 ± 8.65 | 5.05 ± 4.59 | |
| 48 – 72 | 0.18 ± 0.10 | 0.40 ± 0.43 | |
| Subtotal | 74.7 ± 2.3 | 73.0 ± 7.53 | |
| GI contentsc | 0.01 ± 0.00 | 0.02 ± 0.00 | |
| Tissuesc | 0.10 ± 0.018 | 0.12 ± 0.021 | |
| Total recovered | 78.2 ± 2.42 | 77.8 ± 8.41 | |
Mean (±SD) for N= 4 animals.
Combined 0-72 h data shown since excretion is low in urine. Includes cage rinse and urine present in bladder at time of sacrifice.
Collected at study termination which is 72 h.