Table 5.

Disposition of radioactivity 72 h following a single dermal application of [¹⁴C]triclocarban in rats and mice^a

Sample	Percent of Dose Recovered
	Male ratb (1.5%, 7.5 mg/kg)	Male ratb (3%, 15 mg/kg)	Female ratb (1.5%, 7.5 mg/kg)	Male ratc (3%, 15 mg/kg)	Male mouseb (1.5%, 18.75 mg/kg)	Female mouseb (1.5%, 18.75 mg/kg)
Urine	0.12 ± 0.03	0.012 ± 0.014	0.04 ± 0.01	12.3 ± 0.8	1.00 ± 0.70	0.75 ± 0.59
Feces	0.12 ± 0.03	0.079 ± 0.057	0.042 ± 0.013	46.8 ± 5.7	1.56 ± 1.88	0.96 ± 0.86
GI Tract Contents	0.10 ± 0.02	0.02 ± 0.02	0.03 ± 0.02	2.97 ± 0.63	0.26 ± 0.24	0.09 ± 0.08
Tissues	0.031 ± 0.006	0.009 ± 0.009	0.013 ± 0.009	0.52 ± 0.11	0.09 ± 0.07	0.11 ± 0.14
Total Absorbed Dosed	0.37± 0.09	0.12 ± 0.10	0.13 ± 0.05	65.6 ± 8.59	2.91 ± 2.87	1.90 ± 1.49
Dose Site Skine	40.1 ± 2.67	24.3 ± 5.95	26.6 ± 10.0	7.48 ± 3.60	3.79 ± 1.60	1.99 ± 0.59
Total Unabsorbed Dosef	43.6 ± 3.2	72.3 ± 10.1	61.9 ± 10.1	7.8 ± 1.10	77.3 ± 4.7	82.2 ± 2.50
Total Dose Recovered	84.1 ± 3.12	96.7 ± 4.21	88.6 ± 1.95	80.8 ± 6.46	84.0 ± 3.00	86.1 ± 3.53

^aMean ± SD for 4 animals

^bCovered dose site

^cUncovered dose site

^dTotal absorbed dose is the total administered dose recovered in excreta and tissues

^eDose at dose site skin after removing the unabsorbed dose by washing the dose site

^fTotal unabsorbed dose is the total administered dose recovered in dose site wipes, dose site rinses, and dermal appliance (in covered groups only).