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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Xenobiotica. 2020 Jun 24;50(12):1469–1482. doi: 10.1080/00498254.2020.1779391

Table 6.

Summary of metabolites of triclocarban identified in bile from male ratsa

Peak Designationb Retention Time Metabolite Molecular Formula Exact Mass (Calculated) Exact Mass (Observed) Percent of Radioactivity c
1 6.7 Triclocarban-O-glucuronide/O-sulfate C19 H17 Cl3 N2 O12S 600.9490 600.9525 7.2
2 7.2 Triclocarban-O-glucuronide/O-sulfate C19 H17 Cl3 N2 O12S 600.9490 600.9525 4.5
3 7.8 Triclocarban-O-glucuronide C19 H17 Cl3 N2 O8 504.9972 505.0000 11.7
4 8.4 Triclocarban-O-glucuronide C19 H17 Cl3 N2 O8 504.9972 505.0000 41.0
5 9.9, 11.3, 11.4 Triclocarban-O-sulfate C13 H9 Cl3 N2 O5 S 408.9219 408.9242 12.5
6 10.5 Hydroxy triclocarban-O-sulfate C13 H9 Cl3 N2 O6 S 424.9168 424.9193 12.8
7 14.4
15.6
16.2		 Dihydroxy triclocarban
Hydroxy triclocarban
Triclocarban		 C13 H9 Cl3 N2 O3
C13 H9 Cl3 N2 O2
C13 H9 Cl3 N2 O		 344.9601
328.9651
312.9702		 344.9620
328.9669
312.9718		 10.4
a

12-24 h bile was used for metabolite identification work.

b

Peak designation is based on profile given in Figure 3.

c

Percent of radioactivity estimated based on total radioactivity in chromatogram is shown.