Table 7.
Clearance and half-life of triclocarban in rat, mouse, and human hepatocytes in vitroa
| Species | Sex | t1/2 (min) | Clearance (mL/(min*kg)) |
|---|---|---|---|
| Rat | Male | 843 | 4.3 |
| Female | 742 | 5.1 | |
| Mouse | Male | 398 | 10.2 |
| Female | 359 | 9.4 | |
| Human | Male | 372 | 10.1 |
| Female | 362 | 8.1 |
Data shown are based on non-compartmental analysis of mean concentration versus time data of three replicate samples.