Table 2.
Etiologies of Heart Failure for the Patient Cohorts
| Etiology | Total (n=173) | HFrEF (n=47) | HFmrEF-improved (n=59) | HFmrEF-unimproved (n=24) | HFpEF (n=43) | P-value |
|---|---|---|---|---|---|---|
| Ischemic (CAD) | 41 (24%) | 21 (45%) | 9 (15%) | 5 (21%) | 6 (14%) | 0.57 |
| Non-ischemic | 132 (76%) | 26 (55%) | 50 (85%) | 19 (79%) | 37 (86%) | |
| Idiopathic | 96 (56%) | 22 (47%) | 46 (78%) | 11 (46%) | 17 (40%) | <0.01 |
| Amyloid | 1 (1%) | 1 (5%) | ||||
| Congenital | 6 (4%) | 1 (5%) | 5 (12%) | |||
| Hypertrophic | 5 (3%) | 1 (3%) | 2 (9%) | 2 (5%) | ||
| Peripartum | 7 (5%) | 2 (5%) | 1 (2%) | 2 (9%) | 2 (5%) | |
| Restrictive | 1 (1%) | 1 (3%) | ||||
| Valvular | 2 (2%) | 1 (3%) | 1 (5%) | |||
| Other | 13 (8%) | 2 (4%) | 1 (5%) | 10 (24%) | ||
| Mixed | 1 (1%) | 1 (2%) |
CAD: coronary artery disease; EF: ejection fraction; HF: heart failure. Percentages for each EF group are reported in parenthesis. P-values shown are for the difference in frequency between HFmrEF-improved and HFmrEF-unimproved subgroups.