Table 3.
Depicting different cost parameters and their comparison between conventional and newer AEDs groups.
| Cost Parameters in USD Median (Interquartile Range) |
Total PWE (n = 214) |
Newer AEDs (n = 110) |
Conventional AEDs (n = 104) |
p-value between newer and conventional AED groups |
|---|---|---|---|---|
| Direct Medical Cost- | 44.48 (15.20–84.98) |
82.24 (51.00–124.62) |
20.26 (12.76–39.71) |
<0.001 |
| 1.Cost of Medicines | 40.90 (13.64–82.28) |
82.28 (51.00–115.39) |
14.77 (10.36–31.14) |
<0.001 |
| 2.Cost of Hospital stay and admission | 29.41 (29.41–51.46) (n = 4)* |
29.41 (n = 1)* |
29.41 (29.41–73.51) (n = 3)* |
0.28 |
| 3.Cost of Investigations | 5.35 (3.98–25.37) (n = 49)* |
7.14 (3.82–46.11) (n = 20)* |
5.35 (3.98–15.99) (n = 29)* |
0.10 |
| 4.Cost of Adverse effects treatment | 1.34 (0.65–8.69) (n = 11)* |
2.00 (0.39–20.00) (n = 8)* |
1.07 (0.98–2.54) (n = 3)* |
0.14 |
| Direct Non-Medical Cost- | 2.14 (1.20–11.23) |
1.42 (1.20–11.12) |
2.40 (1.20–13.46) |
0.49 |
| 1.Cost of Transportation | 1.68 (1.20–3.79) |
1.39 (1.20–3.66) |
2.14 (1.15–3.97) |
|
| 2.Cost of Lodging | 12.00 (12.00–24.06) (n = 46)* |
15.04 (10.53–24.06) (n = 24)* |
12.00 (12.00–24.06) (n = 22)* |
0.92 |
| 3.Cost of Food | 8.42 (3.84–13.37) (n = 72)* |
8.02 (3.68–20.05) (n = 35)* |
9.62 (4.68–13.37) (n = 37)* |
0.60 |
| Indirect Cost | 18.10 (9.05–35.46) (n = 90)* |
18.10 (9.05–35.46) (n = 40)* |
18.10 (9.05–35.46) (n = 50)* |
0.11 |
|
Total cost of treatment (Direct medical + Direct non-medical + indirect) |
77.90 (33.93–124.65) |
104.77 (79.81–172.44) |
44.04 (20.30–71.35) |
<0.001 |
|
Intangible Cost (Difference between intangible cost at enrolment and end of study) @ |
0 (-368.75–0) |
0 (-403.12 – 108.58) |
0 (-284.39–0) |
– |
*
Cost of this parameter was found only in a some PWE (n).
@
Minus symbol in intangible cost represents a reduction in intangible cost. AEDs: Antiepileptic drugs; PWE: Persons with epilepsy