Skip to main content
. 2020 Oct 23;40(10):BSR20192051. doi: 10.1042/BSR20192051

Table 1. Characteristics of the studies eligible for meta-analysis.

First author Year Country Ethnicity Type of cancer Source of control Genotyping method Case/control Cases Controls HWE Score
Gly388Arg rs351855 G>A GG AG AA G A GG AG AA G A
Ansell 2009 Sweden Caucasian HNSCC PB PCR-RFLP 110/192 61 49 - - 81 111 - - - 9
Bange 2002 Russia Caucasian Breast PB PCR-RFLP 61/123 26 28 7 80 42 55 60 8 170 76 0.114 7
Bange 2002 Germany Caucasian Breast PB PCR-RFLP 84/123 41 34 9 116 52 55 60 8 170 76 0.114 8
Bange 2002 Italy Caucasian Colon cancer PB PCR-RFLP 82/123 37 38 7 112 52 55 60 8 170 76 0.114 8
Batschauer 2011 Brazil Caucasian Breast PB PCR-RFLP 68/85 39 26 3 104 32 47 35 3 129 41 0.249 9
Chen 2018 Taiwan Asian Cervical cancer HB TaqMan 226/335 69 101 56 239 213 96 165 74 357 313 0.845 9
Chou 2017 Taiwan Asian OSCC PB TaqMan 955/1191 225 524 206 974 936 334 596 261 1264 1118 0.873 11
Fang 2013 China Asian NSCLC HB Sequencing 629/729 193 331 105 717 541 163 391 175 717 741 0.049 9
FitzGerald 2009 U.S.A. Caucasian Prostate PB SNPlex 1254/1251 587 544 123 1718 790 631 496 124 1758 744 0.070 15
FitzGerald 2009 U.S.A. African Prostate PB SNPlex 146/80 104 39 3 247 45 60 18 2 138 22 0.646 13
Gao 2014 China Asian NHL NA PCR-RFLP 421/486 117 189 115 423 419 171 240 75 582 390 0.541 11
Heinzle 2012 Austria Caucasian Colon cancer PB TaqMan 85/1660 42 33 10 117 53 802 723 135 2327 993 0.114 10
Ho 2009 Singapore Asian HCC PB Sequencing 58/88 27 17 14 71 45 30 38 20 98 78 0.241 6
Ho 2010 U.K. Caucasian Prostate PB TaqMan 397/291 183 182 32 548 246 150 117 24 417 165 0.860 11
Hosseini 2017 Iran Asian Breast Cancer PB PCR-RFLP 126/160 87 33 6 207 45 54 57 49 165 155 <0.001 6
Jiang 2015 China Asian Breast cancer NA Snapshot 747/716 205 404 138 814 680 270 348 98 888 544 0.398 12
Li 2017 China Asian Cervical Cancer HB PCR-RFLP 162/162 35 79 48 149 175 50 72 40 172 152 0.170 8
Ma 2008 Japan Asian Prostate HB PCR-RFLP 492/179 163 196 133 522 462 67 87 25 221 137 0.701 10
Mawrin 2006 Germany Caucasian Glioma HB PCR-RFLP 94/25 39 51 4 129 59 10 13 2 33 17 0.428 6
Morimoto 2003 Japan Asian Sarcomas NA PCR-RFLP 143/102 54 72 17 180 106 39 50 13 128 76 0.624 10
Naidu 2009 Malaysia Asian Breast HB PCR-RFLP 387/252 179 172 36 530 244 132 105 15 369 135 0.322 9
Nan 2009 U.S.A. Caucasian Skin cancer PB TaqMan 768/833 365 325 78 1055 481 406 343 84 1155 511 0.359 11
Shen 2013 China Asian Gastric cancer PB Sequencing 304/392 118 124 62 360 248 132 188 72 452 332 0.724 11
Sheu 2015 China Asian HCC HB TaqMan 289/595 82 150 57 314 264 159 314 122 632 558 0.146 8
Spinola 2005 Italy Caucasian Lung HB Pyrosequencing 274/401 148 104 22 400 148 193 168 40 554 248 0.699 9
Spinola 2005 Italy Caucasian Breast HB Pyrosequencing 142/220 67 55 20 189 95 112 83 25 307 133 0.117 8
Spinola 2005 Italy Caucasian CRC HB Pyrosequencing 179/220 98 63 18 259 99 112 83 25 307 133 0.117 8
Tanuma 2010 Japan Asian OSCC HB PCR-SSCP 150/100 69 53 28 191 109 42 48 10 132 68 0.487 8
Tsay 2020 Taiwan Asian Cervical cancer HB TaqMan 428/856 114 222 92 450 406 242 426 188 910 802 0.984 10
Ture 2015 Turkey Asian Lung cancer HB PCR-RFLP 124/100 66 47 11 179 69 48 46 6 142 58 0.242 7
Wang 2004 U.S.A. Caucasian Prostate PB PCR-RFLP 284/97 125 117 42 367 201 53 40 4 146 48 0.291 8
Wang 2004 U.S.A. African Prostate PB PCR-RFLP 45/94 37 6 2 80 10 76 18 0 170 18 0.305 7
Whittle 2016 U.S.A. Caucasian Neuroblastoma NA PCR-RFLP 126/114 45 69 12 159 93 50 60 4 160 68 0.006 9
Wimmer 2019 Germany Caucasian HNSCC PB PCR-RFLP 284/123 188 84 12 460 108 55 60 8 170 76 0.114 9
Yang 2012 China Asian HCC HB TaqMan 711/740 216 351 144 783 639 247 361 132 855 625 0.996 10
First author Year Country Ethnicity Type of Cancer Source of control Genotyping method Case/control Cases Controls HWE Score
Val10Ile rs1966265 CC CT TT C T CC CT TT C T
Chen 2018 Taiwan Asian Uterine Cervical HB TaqMan 227/335 61 105 61 227 227 91 168 76 350 320 0.927 9
Chou 2017 Taiwan Asian OSCC PB TaqMan 955/1191 213 514 228 940 970 285 580 326 1150 1232 0.391 11
FitzGerald 2009 U.S.A. Caucasian Prostate PB SNPlex 1259/1254 782 405 72 1969 549 742 447 65 1931 577 0.827 15
FitzGerald 2009 U.S.A. African Prostate PB SNPlex 147/80 132 15 0 279 15 70 10 0 150 10 0.551 13
Jiang 2015 China Asian Breast NA Snapshot 747/716 171 408 168 750 744 126 364 226 616 816 0.322 12
Nan 2009 U.S.A. Caucasian Skin cancer PB TaqMan 753/821 461 251 41 1173 333 507 271 43 1285 357 0.390 11
Sheu 2015 China Asian HCC HB TaqMan 289/595 65 160 64 290 288 151 300 144 602 588 0.835 8
Tsay 2020 Taiwan Asian Cervical cancer HB TaqMan 428/856 95 226 107 416 440 215 420 221 850 862 0.585 10
First author Year Country Ethnicity Type of cancer Source of control Genotyping method Case/control Cases Controls HWE Score
rs7708357 GG GA AA G A GG GA AA G A
Chen 2018 Taiwan Asian Uterine cervical HB TaqMan 227/335 222 4 1 448 6 321 13 1 655 15 0.038 9
Chou 2017 Taiwan Asian OSCC PB TaqMan 955/1191 932 22 1 1886 24 1167 23 1 2357 25 0.015 11
FitzGerald 2009 U.S.A. Caucasian Prostate PB SNPlex 1258/1254 459 632 167 1550 966 507 569 178 1583 925 0.368 15
FitzGerald 2009 U.S.A. African Prostate PB SNPlex 146/78 49 74 23 172 120 34 35 9 103 53 0.999 13
Sheu 2015 China Asian HCC HB TaqMan 289/595 283 5 1 571 7 577 18 0 1172 18 0.708 8
Tsay 2020 Taiwan Asian Cervical cancer HB TaqMan 428/856 416 10 2 842 14 838 17 1 1693 19 0.005 9
First author Year Country Ethnicity Type of cancer Source of control Genotyping method Case/control Cases Controls HWE Score
rs2011077 CC CT TT C T CC CT TT C T
Chen 2018 Taiwan Asian UT-cervical HB TaqMan 227/335 63 102 62 228 226 94 163 78 351 319 0.652 9
Chou 2017 Taiwan Asian OSCC PB TaqMan 955/1191 210 509 236 929 981 288 577 326 1153 1229 0.299 11
Ma 2008 Japan Asian Prostate HB PCR-RFLP 492/179 94 285 113 473 511 11 85 83 107 251 0.075 10
Sheu 2015 China Asian HCC HB TaqMan 289/595 66 159 64 291 287 147 297 151 591 599 0.968 8
Tsay 2020 Taiwan Asian Cervical cancer HB TaqMan 428/856 94 224 110 412 444 217 418 221 852 860 0.495 10
First author Year Country Ethnicity Type of cancer Source of control Genotyping method Case/control Cases Controls HWE Score
rs376618 AA AG GG A G AA AG GG A G
FitzGerald 2009 U.S.A. Caucasian Prostate PB SNPlex 1238/1245 703 448 87 1854 622 712 437 96 1861 629 0.013 15
FitzGerald 2009 U.S.A. African Prostate PB SNPlex 145/80 65 59 21 189 101 38 38 4 114 46 0.154 13
Nan 2009 U.S.A. Caucasian Skin cancer PB TaqMan 762/830 451 273 38 1175 349 468 326 36 1262 398 0.026 11