Table 2. The pooled ORs and 95% CIs for the association between FGFR4 polymorphisms and cancer susceptibility.

	n	Genetic model	Association test			Heterogeneity test			Egger’s test P	Begg’s test P
			OR (95% CI)	Z	P	χ2	I2 (%)	P
Overall
rs351855 G>A	35	AG vs GG	0.97 (0.87–1.07)	0.65	0.514	82.87	60.2	<0.0001	0.012	0.064
		AA vs GG	1.14 (0.95–1.37)	1.39	0.166	116.25	71.6	<0.0001	0.966	0.975
		AG+AA vs GG	0.98 (0.87–1.10)	0.40	0.686	122.33	72.2	<0.0001	0.061	0.129
		AA vs AG+GG	1.15 (0.98–1.33)	1.76	0.79	94.88	65.2	<0.0001	0.476	0.306
		A vs G	1.02 (0.93–1.12)	0.47	0.639	150.59	78.1	<0.0001	0.416	0.293
rs1966265 C>T	8	CT vs CC	1.01 (0.89–1.14)	0.14	0.891	11.12	37.1	0.133	0.739	1.000
		TT vs CC	0.94 (0.77–1.16)	0.56	0.574	14.60	58.9	0.024	0.373	0.176
		CT+TT vs CC	0.98 (0.87–1.11)	0.31	0.759	11.52	39.2	0.118	0.810	0.805
		TT vs CT+CC	0.87 (0.78–0.97)	2.61	0.009	14.07	57.3	0.029	0.094	0.051
		T vs C	0.95 (0.87–1.04)	1.03	0.303	14.24	50.8	0.047	0.722	0.805
rs7708357 G>A	6	AG vs GG	1.17 (0.95–1.44)	1.45	0.146	5.61	10.9	0.346	0.221	0.039
		AA vs GG	1.10 (0.87–1.40)	0.83	0.406	3.61	0.0	0.607	0.143	1.000
		AG+AA vs GG	1.17 (1.02–1.36)	2.19	0.028	4.72	0.0	0.451	0.467	0.091
		AA vs AG+GG	0.98 (0.79–1.21)	0.20	0.840	3.77	0.0	0.583	0.097	0.624
		A vs G	1.08 (0.98–1.20)	1.51	0.132	4.22	0.0	0.518	0.964	0.348
rs2011077 C>T	5	CT vs CC	1.03 (0.79–1.33)	0.21	0.831	11.30	64.6	0.023	0.054	0.014
		TT vs CC	0.79 (0.49–1.25)	1.02	0.309	28.54	86.0	<0.0001	0.228	0.327
		CT+TT vs CC	0.94 (0.69–1.28)	0.39	0.695	17.85	77.6	0.001	0.091	0.050
		TT vs CT+CC	0.79 (0.56–1.13)	1.27	0.203	28.84	86.1	<0.0001	0.681	1.000
		T vs C	0.89 (0.70–1.13)	0.97	0.332	33.89	88.2	<0.0001	0.380	0.327
rs376618 A>G	3	AG vs AA	0.95 (0.85–1.09)	0.56	0.753	1.76	0.0	0.414	0.761	0.602
		GG vs AA	1.04 (0.81–1.33)	0.29	0.771	4.12	51.5	0127	0.067	0.117
		AG+GG vs AA	0.97 (0.76–1.10)	0.45	0.654	1.27	0.0	0.531	0.858	0.602
		GG vs AG+AA	1.19 (0.74–1.93)	0.71	0.476	5.04	60.3	0.080	0.014	0.117
		G vs A	0.99 (0.90–1.09)	0.20	0.841	2.21	9.5	0.331	0.383	0.602