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. 2020 Oct 24;184(1):92–105.e16. doi: 10.1016/j.cell.2020.10.030

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Figure S1 — Genome-wide Loss-of-Function CRISPR Screen Enriched Gene Identification, Related to Figure 1

(A) Scatterplot of guide RNA read counts from A549^ACE2 cells at 3 days post-transduction with the GeCKOv2 library versus read counts from the library plasmid. Read counts ar4e normalized log₂ reads. (B) RRA p-value distribution for all genes in the GeCKOv2 library. (C) Overlap of top-ranked (top 500) genes between 3 different analysis methods (RRA, RIGER, and SBR). 142 genes are found by all 3 methods. (D) Comparison of top-ranked genes between different genome-scale CRISPR screens for SARS-CoV-2 infection.