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Double-targeted knockdown of miR-21 and CXCR4 inhibited the PI3K/AKT and Raf/MEK/ERK pathways in glioma xenograft tissues and cells. (a–c) Related proteins were tested using western blot. P < 0.05, (A) vs. Lv-NC group; (B) vs. anti-miR-21 group; (C) vs. sh-CXCR4 group.
