Fig. 4.

P/Q-type channel-mediated transmission specifically supports the escape response. (A) Example time series showing changes in body curvature during responses triggered by a 20-ms electrical field stimulation (arrows are the start marks) of a wild-type (wt) and P/Q-null fish. Movies were acquired at 1,000 frames per second and analyzed using Flote motion analysis software. (B) Scatterplot comparing curvature of the first bend for wild type, siblings, and P/Q-null mutants. (C) Scatterplot comparing the onset of movement for wild type, siblings, and P/Q-null mutants. Heterozygous siblings were indistinguishable from wild type. n.s., not significant, with P values greater than 0.05. Mean ± SD is indicated in red. ****P < 0.0001.