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. 2020 Oct 10;5(4):185–190. doi: 10.1016/j.ncrna.2020.10.001

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© 2020 [The Author/The Authors]

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Predicted biological functions to be the most impacted by the dysregulated miRNAs included in the signature. (A, B) The impact of the 9 upregulated miRNAs on the KEGG and Gene Ontology (GO) biological pathways, respectively, predicted with DIANA microT-CDS tool. (C, D) The impact of the 6 downregulated miRNAs on the KEGG and Gene Ontology (GO) biological pathways, respectively, predicted with DIANA microT-CDS tool. Heatmap representation of the pathways and the significance (determined from log (p-values)) with each miRNA with red indicating the highest level of significance and yellow the lowest level of significance.