Figure 2.

Anti-Tumor Effect of rMV-SLAMblind in Xenograft Models of TN Breast Cancer Cell Lines

(A and D) MDA-MB-468 (A) or HCC70 (D) cells were transplanted into SCID mice. rMV-EGFP-SLAMblind (filled circle) or medium (open circle) was administered three times at 0, 7, and 14 days after the first inoculation (arrows). Tumor volumes of individual mice (n = 7) for each group as the average + SD. (B and C) Tumors of MDA-MB-468 xenografts were excised at 26 dpi (B), and their weights were measured. (C) Tumor weights are shown as the average + SD. ∗p < 0.05, ∗∗p < 0.01, Welch’s t test.