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(A) Visual predicted check (VPC) for mtDNA methylation, AKG, MMP, and cell vitality. The shaded area represents the 95% confidence interval of the simulated median value. The line represents the median value of observed value. The red scatters represent observed values. (B) Scatter plots of predicted residuals vs. time for mtDNA methylation, AKG, MMP, and cell vitality.
