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Knockdown of circKIF4A inhibits ovarian cancer growth and metastasis in vivo. (A) The growth curves of tumors were shown. (B) Representative images of xenograft tumors (left) and the tumor weight was summarized (right). (C) IHC staining of Ki-67 in ovarian cancer cells transfected with si-NC of si-circKIF4A. (D) Representative images of lung metastatic nodules on HE-stained sections (left) and the number of metastatic nodules was quantified (right). *P < 0.05, **P < 0.01
