Table 3. Oxy-Hb measurement in the DLPFC during spatial working memory task.

	Group	N	Week 0	q	Week 6	q	Δ	ANOVA q
CH11	Placebo	25	0.30 ± 0.61	0.788	0.09 ± 0.93	0.337	-0.20 ± 1.17	0.26
	β-lactolin	24	0.19 ± 0.57		0.48 ± 0.74		0.30 ± 0.85
CH13	Placebo	25	0.47 ± 0.94	0.987	0.36 ± 0.98	0.337	-0.10 ± 1.22	0.26
	β-lactolin	23	0.47 ± 0.81		0.86 ± 1.17†		0.39 ± 0.99
CH14	Placebo	23	-0.35 ± 0.87	0.437	-0.23 ± 0.93	0.543	0.12 ± 1.07	0.585
	β-lactolin	24	-0.03 ± 0.86		-0.04 ± 0.80		0.00 ± 0.99
CH20	Placebo	24	0.00 ± 1.57	0.915	-0.16 ± 1.17	0.543	-0.16 ± 2.07	0.610
	β-lactolin	23	0.16 ± 2.06		0.14 ± 1.25		-0.02 ± 1.96
CH22	Placebo	25	0.46 ± 0.74	0.431	0.54 ± 0.80	0.775	0.07 ± 0.95	0.452
	β-lactolin	24	0.15 ± 0.74		0.47 ± 0.82		0.32 ± 0.99
CH23	Placebo	25	0.36 ± 0.81	0.126	0.18 ± 0.61	0.424	-0.17 ± 0.97	0.045
	β-lactolin	24	-0.22 ± 0.90		0.37 ± 0.37**		0.59 ± 0.94

Oxy-Hb measurement at weeks 0 and 6, and changes between week 0 and week 6 in 6 channels (CH11, CH13, CH14, CH20, CH22 and CH23) during the spatial working memory task. Data are presented as means and ± SD. The number of participants in each channel was represented. Group differences were identified using ANOVA and FDR correlation. Statistically significant differences between baseline and week 6 were identified using paired t-tests. A value of q < 0.05 is considered statistically significant.

ANOVA, analysis of variance; CH, channel; Hb, hemoglobin; FDR, false discovery rate; DLPFC, dorsolateral prefrontal cortex.