Table 1.
Baseline characteristics of the study participants.
| − | All |
CAD |
||
|---|---|---|---|---|
| (n = 680) | YES (n = 145) | NO (n = 535) | p-value | |
| Age (years) | 50 ± 18 | 61 ± 13 | 47 ± 18 | <2 × 10−16 |
| Male | 344 (51%) | 104 (72%) | 240 (45%) | 1.3 × 10−8 |
| Body weight (kg) | 62 ± 14 | 67 ± 14 | 61 ± 14 | 2.8 × 10−6 |
| Hypertension | 247 (36%) | 115 (79%) | 132 (25%) | <2 × 10−16 |
| Diabetes | 125 (18%) | 53 (37%) | 72 (13%) | 4.2 × 10−10 |
| Smoking | 242 (36%) | 111 (77%) | 131 (24%) | <2 × 10−16 |
| Total cholesterol (mg/dL) | 264 ± 78 | 271 ± 74 | 255 ± 79 | 9.6 × 10−4 |
| Triglyceride (mg/dL) | 117 [78–182] | 110 [74–181] | 128 [100–182] | 0.08 |
| HDL cholesterol (mg/dL) | 53 ± 17 | 45 ± 12 | 55 ± 18 | <2 × 10−16 |
| LDL cholesterol (mg/dL) | 175 ± 72 | 179 ± 71 | 168 ± 73 | 3.8 × 10−4 |
| Family history | 180 (26%) | 28 (19%) | 152 (28%) | 0.04 |
| FH mutation | 175 (26%) | 27 (19%) | 148 (28%) | 0.04 |
| Achilles tendon thickness (mm) | 7.2 ± 3.0 | 7.9 ± 3.6 | 7.0 ± 2.8 | 0.008 |
FH, familial hypercholesterolemia; CAD, coronary artery disease.