Table 5.
Radiotherapy technique and selected dose-volume parameters for the whole heart and selected cardiac substructures
| Parameter | 3D-CRT | t-IMRT | p value* |
|---|---|---|---|
| MWHD [Gy] | 1.90 (0.61–4.14) | 2.13 (1.06–4.4) | < 0.005 |
| LV-Dmean [Gy] | 2.98 (0.78–8.03) | 3.22 (1.31–7.25) | < 0.005 |
| LV-V5 Gy [%] | 8.67 (0–26.3) | 9.21 (0–26.02) | 0.455 |
| LV-V23 Gy [%] | 2.46 (0–14.32) | 1.86 (0–10.58) | 0.003 |
| LV anterior-Dmean [Gy] | 5.00 (1.27–20.17) | 5.42 (1.94–19.18) | < 0.005 |
| LV apical-Dmean [Gy] | 8.97 (1.22–24.89) | 8.47 (1.64–22.16) | < 0.005 |
| LADCA-Dmean [Gy] | 8.20 (1.23–27.92) | 8.39 (1.8–27.62) | < 0.005 |
| LADCA-V30 Gy [%] | 5.39 (0–66.34) | 2.01 (0–84.20) | < 0.005 |
| LADCA-V40 Gy [%] | 0 (0–37.8) | 0 (0–43.09) | < 0.005 |
| LADCA-prox-Dmean [Gy] | 2.17 (0.62–8.68) | 2.66 (1.22–12.43) | < 0.005 |
| LADCA-mid-Dmean [Gy] | 9.63 (1.67–40.07) | 11.05 (2.26–39.63) | 0.956 |
| LADCA-dist-Dmean [Gy] | 13.73 (1.44–41.11) | 15.93 (2.03–3.89) | 0.132 |
*Wilcoxon signed-rank test; 3D-CRT = three-dimensional conformal radiotherapy; dist = distal; Dmean = mean dose; Gy = Gray; LADCA = left anterior descending artery; LV = left ventricle; mid = middle; MWHD = whole heart mean dose; prox = proximal; t-IMRT = tangential intensity modulated radiation therapy; Vx Gy = fractional volume receiving x Gy