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The oxygen level in the optic nerve (oxygenON) is a product of the oxygen-carrying capacity in the blood (oxygenB) and the amount of blood flow to the optic nerve (perfusion). The hematocrit is a proxy for oxygen in the blood (oxygenB). The perfusion pressure is the difference between the blood pressure and tissue pressure. The risk of posterior ischemic optic neuropathy is inversely related to hematocrit × (blood pressure–tissue perfusion pressure)
