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. 2020 Oct 19;12:10311–10319. doi: 10.2147/CMAR.S266807

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© 2020 Zhang et al.

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lnc-NLIPMT inhibits the growth of PTC cells in vitro. (A) The overexpression of lnc-NLIPMT(oe-NLIPMT) was confirmed by qRT-PCR. lnc-NLIPMT expression was dramatically increased in TPC-1 and B-CPAP transfected with the NLIPMT plasmid, compared with the negative control (NC). (B) The knockdown of lnc-NLIPMT in TPC-1 cell transfected with si-NLIPMT compared with NC was validated by qRT-PCR. (C) CCK-8 assays and (D) colony formation assays show growth inhibition of TPC-1 and B-CPAP cells overexpressing lnc-NLIPMT compared with their corresponding control cells. (E) CCK-8 assays and (F) colony formation assays showing down-regulation of lnc-NLIPMT in TPC-1 cell stimulates proliferation compared with control cells. (P-values were calculated by Student’s t-test, *P < 0.05; **P < 0.01; ***P < 0.001; ****P<0.0001).