Table 2.
Primary Outcome Characteristics and Changes from Baseline Between and Within Groups
| Outcomes | Group A | Group B | Group C | Value of Pairwise Comparison | |||||
|---|---|---|---|---|---|---|---|---|---|
| (N=64) | (N=68) | (N=76) | Group A vs Group B | Group A vs Group C | Group B vs Group C | ||||
| Difference (95% Cl)a | Pb | Difference (95% Cl)a | Pb | Difference (95% Cl)a | Pb | ||||
| Duration rating of CMSS, meridian (Q1-Q3) | |||||||||
| 0 month | 18.00 (15.00, 20.00) | 18.00 (15.00, 20.00) | 17.50 (12.00, 23.00) | – | – | – | – | – | – |
| 1 month | 9.00 (6.50, 11.00) | 12.00 (9.00, 16.00) | 18.00 (13.00, 22.00) | −3.17 (−4.39, −1.96) | <0.001 | −8.28 (−9.52, −7.03) | <0.001 | −5.11 (−6.25, −3.96) | <0.001 |
| 2 month | 5.00 (3.00, 6.00) | 7.00 (5.00, 10.00) | 17.00 (13.00, 21.00) | −2.64 (−4.30, −0.97) | <0.001 | −11.29 (−12.99, − 9.58) | <0.001 | −8.65 (−10.21, −7.08) | <0.001 |
| 3 month | 2.00 (1.00, 3.00) | 6.00 (3.00, 9.00) | 19.00 (12.00, 21.50) | −3.44 (−5.31, −1.57) | <0.001 | −13.80 (−15.71,−11.88) | <0.001 | −10.36 (−12.11, −8.60) | <0.001 |
| 4 month | 1.00 (1.00, 2.00) | 3.00 (2.00, 6.00) | – | −2.43 (−4.28, −0.59) | 0.010 | – | – | – | – |
| 5 month | 1.00 (0.00, 1.00) | 3.00 (1.00, 6.00) | – | −2.43 (−4.31, −0.55) | 0.012 | – | – | – | – |
| 6 month | 0.00 (0.00, 1.00) | 3.00 (1.00, 5.00) | – | −2.36 (−4.19, −0.52) | 0.012 | – | – | – | – |
| Severity rating of CMSS, meridian (Q1-Q3) | |||||||||
| 0 month | 14.50 (12.00, 17.00) | 14.00 (12.00, 17.00) | 14.00 (10.00, 18.50) | – | – | – | – | – | – |
| 1 month | 9.00 (8.00, 11.00) | 9.00 (7.00, 11.00) | 14.00 (11.00, 17.50) | 0.22 (−0.92, 1.35) | 1.000 | −5.02 (−6.17, −3.87) | <0.001 | −5.24 (−6.27, −4.20) | <0.001 |
| 2 month | 6.00 (4.00, 7.50) | 4.00 (3.00, 6.50) | 14.00 (11.00, 17.50) | 1.16 (−0.36, 2.67) | 0.203 | −7.80 (−9.35, −6.26) | <0.001 | −8.96 (−10.35, −7.57) | <0.001 |
| 3 month | 3.00 (2.50, 4.00) | 3.00 (2.00, 6.00) | 14.00 (11.50, 18.00) | −0.40 (−2.13, 1.33) | 1.000 | −10.72 (−12.47, −8.96) | <0.001 | −10.31 (−11.89, −8.73) | <0.001 |
| 4 month | 2.00 (2.00, 3.00) | 3.00 (2.00, 5.00) | – | −0.82 (−2.34, 0.70) | 0.287 | – | – | – | – |
| 5 month | 2.00 (1.00, 3.00) | 3.00 (2.00, 5.50) | – | −1.10 (−2.68, 0.47) | 0.168 | – | – | – | – |
| 6 month | 2.00 (1.00, 3.00) | 3.00 (1.50, 5.50) | – | −1.40 (−2.94, 0.14) | 0.074 | – | – | – | – |
Notes: aLeast squared mean adjusted for duration of dysmenorrhea symptoms and severity of dysmenorrhea symptoms at baseline between and within groups (Bonferroni adjusted). bMultiple comparison results adjusted using the Bonferroni correction.