Table 3.
Characteristics and Changes in Secondary Outcomes from Baseline and Multiple Comparisons
| Outcomes | (N=64) | (N=68) | (N=76) | Value of Pairwise Comparison | |||||
|---|---|---|---|---|---|---|---|---|---|
| Group A | Group B | Group C | Group A vs Group B | Group A vs Group C | Group B vs Group C | ||||
| Difference (95% Cl)a | Pb | Difference (95% Cl)a | Pb | Difference (95% Cl)a | Pb | ||||
| Pain intensity rating of VAS, meridian (Q1-Q3) | |||||||||
| 0 month | 6.00 (5.00, 7.00) | 6.00 (5.00, 7.00) | 5.00 (4.00, 7.00) | – | – | – | – | – | – |
| 1 month | 4.00 (3.00, 5.00) | 4.00 (3.00, 5.00) | 5.00 (4.00, 6.50) | 0.06 (−0.32, 0.44) | 1.000 | −1.63 (−2.01, −1.24) | <0.001 | −1.69 (−2.04, −1.33) | <0.001 |
| 2 month | 2.00 (2.00, 3.00) | 3.00 (2.00, 3.00) | 5.50 (4.00, 7.00) | −0.07 (−0.60, 0.46) | 1.000 | −3.01 (−3.54, −2.48) | <0.001 | −2.94 (−3.43, −2.45) | <0.001 |
| 3 month | 0.50 (0.00, 1.00) | 2.00 (0.00, 3.00) | 6.00 (4.00, 7.00) | −1.01 (−1.68, −0.34) | 0.001 | −4.75 (−5.43, −4.08) | <0.001 | −3.75 (−4.37, −3.12) | <0.001 |
| 4 month | 0.50 (0.00, 1.00) | 2.00 (0.00, 3.00) | – | −0.85 (−1.49, −0.21) | 0.010 | – | – | – | – |
| 5 month | 0.00 (0.00, 1.00) | 1.00 (0.00, 3.00) | – | −0.85 (−1.51, −0.20) | 0.011 | – | – | – | – |
| 6 month | 0.00 (0.00, 1.00) | 1.00 (0.00, 3.00) | – | −0.96 (−1.64, −0.27) | 0.007 | – | – | – | – |
| Anxiety measured by SAS, meridian (Q1-Q3) | |||||||||
| 0 month | 50.00 (40.00, 52.50) | 50.00 (39.38, 53.75) | 41.25 (33.75, 52.50) | – | – | – | – | – | – |
| 3 month | 37.50 (32.50, 40.00) | 38.75 (35.00, 41.25) | 43.75 (36.88, 52.50) | −0.05 (−2.27, 2.16) | 1.000 | −9.88 (−12.08, −7.67) | <0.001 | −9.82 (−11.87, −7.77) | <0.001 |
| Depression measured by SDS, meridian (Q1-Q3) | |||||||||
| 0 month | 50.00 (41.38, 55.63) | 50.00 (42.50, 54.38) | 50.00 (41.38, 55.63) | – | – | – | – | – | – |
| 3 month | 38.75 (33.75, 41.25) | 39.38 (35.00, 43.75) | 38.75 (33.75, 41.25) | −0.98 (−3.26, 1.30) | 0.908 | −8.86 (−11.12, −6.59) | <0.001 | −7.88 (−9.99, −5.77) | <0.001 |
Notes: aLeast squared mean adjusted for VAS score, depression score, anxiety score at baseline between and within groups (Bonferroni adjusted). bMultiple comparisons adjusted using the Bonferroni correction.