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. 2020 Oct 19;12:161–170. doi: 10.2147/ORR.S272980

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PGIC by KL Grade. PGIC indicates Patient Global Impression of Change on a 7-point Likert Scale. Patients with Kellgren–Lawrence (KL) grade 3 knee osteoarthritis (OA) reported greater improvement at 3, 6, and 12 months compared with those with KL grade 4 knee OA (* denotes P < 0.05).