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. 2020 Oct 16;15:7995–8018. doi: 10.2147/IJN.S270242

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© 2020 Radwan et al.

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Effect of GA-CNPs on cellular uptake and cytotoxicity activities in aHSCs; (A) microscopic fluorescent image showing aHSCs uptake of Rhodamine-loaded-CNP, (B, C) cytotoxicity/antiproliferative activity of the free GA and GA-CNPs against (B) aHSCs and (C) primary hepatocytes after 48 h exposure. Each experiment is performed in triplicate (n=3).

Abbreviations: GA, Gallic acid; aHSCs, activated hepatic stellate cells; ANCNP, Anionic zein/phospholipid composite nanoparticles; CACNP, Cationic zein/phospholipid composite nanoparticles; CACNP/VA, Cationic zein/phospholipid composite nanoparticles coupled with vitamin A.