Table 1.
Effects on differentiation in neural stem cells exposed to 100 µM BMAA and their daughter cells (D1 and D2).
Cells | Control | BMAA |
---|---|---|
Exposed neural stem cells | ||
Neurons | 43.38 ± 4.15 | 22.9 ± 1.92*** |
Astrocytes | 24.38 ± 3.25 | 27.49 ± 13 |
Oligodendrocytes | 10.24 ± 3.45 | 4.17 ± 1.91* |
Undifferentiated cells | 21.26 ± 4.94 | 46.27 ± 7.73* |
D1 daughter cells | ||
Neurons | 36.98 ± 8.88 | 17.74 ± 7* |
Astrocytes | 25.34 ± 3.97 | 11.31 ± 2.23* |
Oligodendrocytes | 13.84 ± 6.85 | 11.74 ± 2.5 |
Undifferentiated cells | 22.83 ± 12 | 59.2 ± 8** |
D2 daughter cells | ||
Neurons | 40.73 ± 5.52 | 22.68 ± 3.48** |
Astrocytes | 22.67 ± 5.75 | 29.23 ± 16 |
Oligodendrocytes | 25.28 ± | 10 ± 2.06** |
Undifferentiated cells | 11.4 ± 5.9 | 40.02 ± 12* |
Results are expressed as percentage for total events (10,000 events).
Statistically significant differences from control are indicated as follow: ***p < 0.001; **p < 0.01, and *p < 0.05 (Student’s t-test).