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. 2020 Oct 24;11(10):911. doi: 10.1038/s41419-020-03071-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Colony formation assay indicated the clones’ number of CC cells. SiHa cells were transfected with METTL3 knockdown, and CaSki cells were transfected with METTL3 overexpression. b CCK-8 assay illustrated the proliferative ability with METTL3 knockdown or METTL3 overexpression. c Flow cytometry for apoptosis indicated the apoptotic rate with METTL3 knockdown and METTL3 overexpression. d Flow cytometry for cell-cycle analysis demonstrated the cellular distribution at G0/G1, S, G2/M phase. Data are displayed as mean ± standard deviation. **p < 0.01 vs. control. *p < 0.05 vs. control.