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. 2020 Oct 24;11(10):912. doi: 10.1038/s41419-020-03121-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — A In different breast cancer cell lines, Notch3 was highly expressed in luminal breast cancer cells and associated with the expression of the epithelial marker, E-cadherin, while the expression of FSCN1 was high in TNBC cells and related to the expression of mesenchymal markers, Vimentin, and Slug. B. The representative images of FSCN1 and Notch3 in patients with a luminal subtype of breast cancers, indicates that the expression of FSCN1 was low, negatively related to high levels of Notch3 in such patients. C The representative images of FSCN1 and Notch3 in patients with TNBC, reveals that the expression of FSNC1 is significantly high, also negatively related to low levels of Notch3 in such patients. (Magnification: 200× for the upper one, and 400× for the low one).