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. 2020 Oct 21;14:4387–4405. doi: 10.2147/DDDT.S273612

Table 1.

Enteric-Coated Nanoparticle Formulations for Non-Colorectal Cancer

No Polymer Active Ingredient Application Ref
1. Propylene glycol alginate sodium sulfate Potential enteric delivery system 90
2. Copper-substituted mesoporous silica 16-Hydroxy-cleroda-3,13-dien-16,15-olide (HCD) Controlled anti-glioma drug delivery 91
3. Starch and chitosan Withania coagulans extract Enteric extract delivery system 92
4. Polylactic acid (PLA), polyvinyl alcohol, poloxamer 188 β-galactosidase Protection on enzymatic degradation 93
5. PLGA, lipid, PEG Insulin Oral insulin delivery system 94
6. Polyacrylic resin II (PRII) and solid lipid (polyvinyl alcohol and octadecanoic acid) Enrofloxacin (ENR) Enteric delivery and light protector system 51
7. Deoxycholic acid-conjugated chitosan Insulin Oral insulin delivery system 95
8. Hydroxypropyl methylcellulose and Eudragit® L100 Darunavir Enteric antivirus delivery system 96
9. (methoxy-polyethylene glycol)-b-poly(D,L-lactide-co-glycolide)-b-poly(L-lysine) Peptide Val-Leu-Pro-Val-Pro-Arg Enteric peptide delivery system 97
10. Hyaluronic acid, chitosan, and Eudragit® L-100 Insulin Oral insulin delivery system 98
11. Chitosan and Eudragit® L-100 Bovine serum albumin (BSA) Oral protein vaccine delivery system 99
12. Deoxycholic acid conjugated PEGylated polyhydroxybutyrate Insulin Oral insulin delivery system 100
13. Hyaluronic acid (HA) Insulin Oral insulin delivery system 101
14. Guar gum and Eudragit® L30D Amphotericin B Antileishmanial drug delivery system 102
15. Compritol 888 ATO, cetyl palmitate, stearic acid, Dynasan® 114, Dynasan® 116, Dynasan® 118, Gelucire® 50/13, Softisan® 154, lauric acid, glyceril monostearate, glyceril trioleat, Labrafil® M-2151 CS, Labrafac® WL 1349, corn oil, sesame oil, sthyl oleat, oleic acid, Eudragit® S100 Budesonide Inflammatory Bowel Disease 103
16. Gelatin, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), monophosphoryl lipid A, glycerol tripalmitate, and cholesterol HBsAg Oral vaccine delivery system 104
17. Eudragit® S-100 and Eudragit® L-100 Sulfasalazine Oral-specific delivery 105
18. Glyceryl monooleate and Eudragit® L100-55 Pravastatin sodium (PVS) Duodenum-triggered delivery 106
19. Eudragit® L100-55 and polyvinyl alcohol Nifedipine Oral pH-sensitive delivery 107
20. N-(2-hydroxy)-propyl-3-trimethylammonium chloride modified chitosan (HTCC) and sodium tripolyphosphate (TPP) Insulin Oral insulin delivery system 108
21. Mesoporous silica Safranin O Colonic targeted delivery system 109
22. Monomethoxyl poly(ethylene glycol)-b-poly(L-lactide-co-glycolide) Growth factor Enteric protein delivery system 110
23. Hydroxypropyl methylcellulose phthalate (HPMCP) Omeprazole Enteric drug delivery system 111
24. Hydroxypropyl methylcellulose phthalate (HP55), poly(lactic-co-glycolic acid) (PLGA), and Eurdragit® RS Insulin Oral insulin delivery system 112
25. Polyacrylic acid Papain Small intestine targeted delivery system 113
26. Polyethylene imine Insulin Oral insulin delivery system 114
27. Mesoporous silica and polyacrylic acid Metoprolol tartrate Enteric delivery and sustained release system 115
28. Eudragit® RS100 and poly(lactic-co-glycolic acid) (PLGA) Lansoprazole Enteric delivery and sustained release system 116
29. Eudragit® L100 Darunavir Enteric antivirus delivery system 117
30. Methacrylic acid-methyl methacrylate and chitosan Recombinant human keratinocyte growth factor (rHuKGF) Enteric protein delivery system 118
31. Phospholipon® 90H, Arlacel® 1689, Crodamol® CP-PA-(SG), and Eudragit® S100 Lipo-endomorphin-1 Enteric peptide delivery system 119
32. Compritol 888 ATO (COMP) and Poloxamer 188 (P-188) Carvedilol Lymphatic absorption 120
33. poly(g-glutamic acid) and chitosan Exendin-4 Enteric peptide delivery system 121
34. Poly(methacrylic acid)-polysorbate 80-grafted-starch terpolymer and ethylcellulose Diltiazem Enteric delivery and controlled release system 122
35. Pluronic Efavirenz Microfold cells (M-cells) targeted delivery system 123
36. Poly(D,L-lactide-co-glycolide) and Eudragit S100 Eluxadoline Enteric delivery and sustained release system 124
37. Alginate and chitosan Goat anti-mouse IgG peroxidise conjugate Oral vaccine delivery system 125
38. Hydroxypropyl methylcellulose phthalate (HP55) Insulin Oral insulin delivery system 126
39. Diethylene triamine pentaacetic acid and poly(γ-glutamic acid) Insulin Oral insulin delivery system 127
40. Folate-chitosan 5-fluourouacil (5-FU) and leucovorin (LV) Multiple drug and targeted delivery system 128
41. Poly(lactic-co-glycolic acid) Docetaxel Lymphatic absorption 129
42. Chitosan and Eudragit L-100 Insulin Oral insulin delivery system 130
43. Acrylic acid and methacrylic Rifampicin Sustained release and mucoadhesive delivery 131
44. Poloxamer 188, polyvinyl alcohol, and polyacryl resin II Tilmicosin Prevent gastrointestinal degradation 132