Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 20;12:10389–10396. doi: 10.2147/CMAR.S273072

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Zhang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Circular RNA_103598 promoted cell proliferation and OVV-mediated antitumor effect in PTC via sponging miR-23a-3p. (A) Potential targeting sites of circRNA_103598 and miR-23a-3p. (B) Relative luciferase activity–dual luciferase report assay. (C) Expression of miR-23a-3p was increased by silencing circRNA_103598 in BHP5-16 and TPC-1 cells. (D) qRT-PCR assay of miR-23a-3p expression in PTC tissues and normal tissues. (E) Expression of miR-23a-33p was negatively correlated with circRNA_103598 expression. Suppression of PTC cell proliferation (F) and decreased IC₅₀ values of OVV (G) caused by silencing circRNA_103598 could be reversed by transfecting miR-23a-3p inhibitor. *p<0.05.