Table 1.
Heterogeneity Tests and MR-Egger Intercept of Short Sleep Duration and Frequent Insomnia Symptoms Causally Linked to Ischemic Stroke and Its Subtypes
Exposure and Outcome | Cochran’s Q | p valuea | Intercept | p valueb |
---|---|---|---|---|
Short sleep duration | ||||
Large artery stroke | 26.47 | 0.438 | −0.011 | 0.618 |
Small vessel stroke | 24.19 | 0.508 | 0.015 | 0.480 |
Cardioembolic stroke | 32.20 | 0.152 | −0.008 | 0.705 |
Any ischemic stroke | 18.15 | 0.836 | −0.002 | 0.813 |
Frequent insomnia symptoms | ||||
Large artery stroke | 76.02 | 0.032 | −4.74×10−3 | 0.692 |
Small vessel stroke | 68.84 | 0.099 | 0.004 | 0.736 |
Cardioembolic stroke | 52.84 | 0.558 | −2.60×10−4 | 0.974 |
Any ischemic stroke | 74.34 | 0.042 | 0.004 | 0.445 |
Notes: ap value for heterogeneity tests; bp value for MR-Egger intercept.
Abbreviation: MR, Mendelian randomization.