Table 2.
In Silico Validation for the top 20 ranked genes for breast cancer.
| Gene | PolySearch2 (Z Score) | COREMINE (Statistical significance) | MalaCards (Score) |
|---|---|---|---|
| CCND1 | 49.43 | 5.12 × 10−5 | 86.94 |
| CDKN2A | 4.59 | 7.97 × 10−4 | 33.58 |
| MYC | 26.82 | 1.59 × 10−4 | 72.97 |
| ESR1 | 30.11 | 3.78 × 10−6 | 1165.88 |
| XRCC5 | 13.23 | 1.51 × 10−2 | – |
| CHEK2 | 14.01 | 1.30 × 10−4 | 1461.53 |
| XRCC6 | – | 1.43 × 10−2 | – |
| EXO1 | 1.23 | 0.135 | – |
| RNASEH2A | 4.71 | 0.502 | – |
| BRCA2 | 11.95 | 3.39 × 10−6 | 1500.88 |
| ADSL | 2.69 | 0.350 | – |
| PPP2R1B | 5.42 | 2.44 × 10−2 | – |
| JUND | – | 7.16 × 10−2 | – |
| PES1 | 2.39 | 1.83 × 10−2 | – |
| PSAT1 | 1.45 | 1.14 × 10−2 | – |
| ADCY3 | 8.19 | 0.335 | – |
| SEPT9 | – | 0.193 | – |
| STAT3 | 20.75 | 3.05 × 10−4 | 42.45 |
| HDGF | – | 0.232 | – |
| EP300 | 1.82 | 1.72 × 10−3 | 50.25 |
Footnotes: - indicates that the value is not available.