Table 3.
Summary of Associations of Clinical Parameters as Outcomes with the Main Independent Variable (Changes of MPR) using GEE (for HbA1c, SBP and DBP) and Logistic Regression (for LDL-C).
| Clinical parameter | Factors | Odds ratio (95% CI) | P-value | |
|---|---|---|---|---|
| Decrease in HbA1ca | Changes of MPR of OHGA | 1.02 (1.00-1.04) | .060 | |
| Group | Control | 1.00 | .497 | |
| MDMPS | 1.28 (0.63-2.60) | |||
| Decrease in SBPb | Changes of MPR of HTN medication | 0.99 (0.98-1.01) | .305 | |
| Group | Control | 1.00 | .411 | |
| MDMPS | 0.80 (0.47-1.36) | |||
| Decrease in DBPb | Changes of MPR of HTN medication | 0.99 (0.97-1.00) | .132 | |
| Group | Control | 1.00 | .870 | |
| MDMPS | 0.96 (0.55-1.65) | |||
| Decrease in LDL-Cc | Changes of MPR of HLD medication | 1.04 (1.01-1.07) | .007** | |
| Group | Control | 1.00 | .359 | |
| MDMPS | 0.65 (0.26-1.64) | |||
Abbreviations: DBP: diastolic blood pressure; DM: type 2 diabetes mellitus; GEE: generalized estimating equation; HbA1c: glycated hemoglobin; HLD: hyperlipidemia; HTN: hypertension; LDL-C: low-density lipoprotein-cholesterol; MPR: medication possession ratio; OHGA: oral hypoglycemic agent; SBP: systolic blood pressure.
Covariates in GEE: Time (6 or 12-month index period), gender, race, use of insulin, age, baseline HbA1c, baseline MPR of OHGA, baseline number of chronic medications and baseline number of OHGA.
Covariates in GEE: Time (6 or 12-month index period), gender, race, age, baseline SBP or DBP, baseline MPR of HTN medications, baseline number of chronic medications and baseline number of HTN medications.
Covariates in Logistic regression: Gender, race, age, baseline LDL-C, baseline MPR of HLD medications, baseline number of chronic medications and baseline number of HLD medications.
P < .05.