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. 2020 Oct 1;27(10):1068–1085. doi: 10.5551/jat.52993

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2020 Japan Atherosclerosis Society

This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License.http://creativecommons.org/licenses/by-nc-sa/3.0/

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Fig. 8. — Immunochemistry analysis of IGFBP6 in histologically stable and unstable plaques

A. IGFBP6-positive area (brown) is significantly decreased in the unstable plaque compared with that in the stable plaque (×10) (****p < .0001) B. Colocalization of CD68⁺ macrophages in the border between the fibrous cap and necrotic core, in the area where IGFBP6 is expressed (×10). The black rectangle indicates the local enlarged view (×40). C. CD31⁺ endothelial cells are colocalized with IGFBP6 (× 10). The black rectangle indicates the local enlarged view (×40).