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. Author manuscript; available in PMC: 2020 Oct 26.
Published in final edited form as: Curr Opin Endocrinol Diabetes Obes. 2020 Aug;27(4):207–214. doi: 10.1097/MED.0000000000000551

Table 1.

Pediatric type 1 diabetes low-density lipoprotein cholesterol management guidelines

2020 ADA SOMC 2018 ISPAD Guidelines 2019 AHA Statement
LDL-C goal LDL-C <100 mg/dL (2.6 mmol/L). LDL-C <100 mg/dL (2.6 mmol/L). LDL-C <100 mg/dL (2.6 mmol/L).
Pharmacological therapy From age 10 years, consider statin if despite lifestyle changes, LDL-C >160 mg/dL (4.1 mmol/L) or LDL-C >130 mg/dL (3.4 mmol/L) with one or more ASCVD risk factors. From age 11 years, statins should be started if LDL-C ≥130 mg/dL despite interventions to improve metabolic control and lifestyle. From age 10 years, initiate statin therapy and lifestyle change if LDL-C ≥130 mg/dL.
Consider adding cholesterol absorption inhibitor if LDL-C goal not met with statin.

ASCVD, atherosclerotic cardiovascular disease; LDL-C, low-density lipoprotein cholesterol.