Fig. 2.

Network of viral-host protein–protein interactions Network of protein interactions for proteins of the Zika virus (indicated as octogonal nodes with thick red borders) with proteins with a degree higher than 1. The nodes (circle with black borders) correspond to human proteins identified by AP-MS data analysis. Nodes are coloured based on their associated gene ontology as indicated on the bottom left corner. Edges represent confident interactions between two proteins as follows: solid black lines are interactions only identified in the current analysis; dashed black lines are interactions shared with the original study (Shah, et al.); and full grey lines are host–host protein interactions retrieved from the STRING database. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)