Table 4.

Multivariate linear regression analyses showing significant predictor of the TMAO

Model 1 (young ACS and control group)	Unstandardized coefficients		Standardized coefficients
	B	SE	β	t	P
Age	0.641	0.877	0.080	0.732	0.467
Gender	19.616	14.392	0.153	1.363	0.177
BMI	4.688	2.427	0.212	1.931	0.057
HT	7.526	17.229	0.047	0.437	0.664
DM	14.469	24.692	0.062	0.586	0.560
Smoking	36.184	17.811	0.211	2.032	0.046
SBP	0.462	0.518	0.093	0.891	0.376
Creatinine	43.358	36.584	0.139	1.185	0.240
Total-C	0.148	0.220	0.082	0.674	0.502
LDL	0.188	0.242	0.094	0.776	0.440
HDL	0.036	0.470	0.009	.077	0.939
Triglyceride	0.013	0.055	0.028	0.242	0.809
hsCRP	0.260	0.550	0.054	0.473	0.637
Young ACS	50.046	16.748	0.399	2.988	0.004
Model 2 (young and elderly ACS)
Age	2.309	1.870	0.387	1.235	0.221
Gender	4.627	15.389	0.035	0.301	0.765
BMI	0.664	3.329	0.026	0.200	0.842
HT	3.896	19.549	0.024	0.199	0.843
DM	10.991	22.386	0.053	0.491	0.625
Smoking	1.832	21.310	0.011	0.086	0.932
SBP	0.476	0.530	0.100	0.899	0.371
Creatinine	13.381	36.058	0.041	0.371	0.712
Total-C	0.362	0.210	0.272	1.727	0.088
LDL	0.383	0.221	0.274	1.736	0.087
Triglyceride	0.033	0.046	0.083	0.718	0.475
hsCRP	0.180	0.546	0.074	0.346	0.536
Young ACS	28.275	13.139	0.230	2.152	0.035

B - unstandardized regression coefficient; SE - standard error; β- standardized β coefficient; BMI - body mass index; DM - diabetes mellitus; HT - hypertension; hsCRP - high-sensitivity C-reactive protein; total-C - total cholesterol; SBP - systolic blood pressure; TMAO - trimethylamine N-oxide; LDL - low-density lipoprotein; HDL - high-density lipoprotein;

ACS - acute coronary syndrome