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The Grade of Prostatic Intraepithelial Neoplasia (PIN) of NKX3.1 KO Mice in 16 and 24 Weeks.
| Age | Genotype | PIN grade | Detection rate (%) | ||
|---|---|---|---|---|---|
| DLP | VP | AP | |||
| 16 weeks | WT | PIN 1 | - | - | 1.5 |
| PIN 2 | - | - | - | ||
| HT | PIN 1 | - | - | - | |
| PIN 2 | - | - | - | ||
| KO | PIN 1 | - | - | 25 | |
| PIN 2 | - | - | - | ||
| 24 weeks | WT | PIN 1 | 33 | - | 33 |
| PIN 2 | - | - | - | ||
| HT | PIN 1 | 33 | 33 | 33 | |
| PIN 2 | - | - | - | ||
| KO | PIN 1 | - | 66 | 50 | |
| PIN 2 | 66 | - | 50 | ||
Note: PIN 3 was not detected in any tissue samples of prostate.
