Table 3.
Lesion count (sensitivity in %) MRI scoring
| Histology |
MRI rating |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Lesion type | n | T1 pro (%) | T1 retro (%) | PD/T2 pro (%) | PD/T2 retro (%) | FLAIR pro (%) | FLAIR retro (%) | DIR pro (%) | DIR retro (%) | PSIR pro (%) | PSIR retro (%) |
| Type I | 7 | 2 (28.6) | 3 (42.9) | – | 2 (28.6) | 1 (14.3) | 3 (42.9) | 4 (57.1) | 5 (71.4) | 3 (42.9) | 6 (85.8) |
| Type II | 56 | 4 (7.1) | 8 (14.3) | 2 (3.6) | 5 (8.9) | 1 (1.8) | 7 (12.5) | 7 (12.5) | 12 (21.4) | 7 (12.5) | 17 (30.4) |
| Type III | 141 | 13 (9.2) | 46 (32.6) | 9 (6.4) | 34 (24.1) | 6 (4.3) | 30 (21.3) | 33 (23.4) | 63 (44.7) | 32 (22.7) | 84 (59.6) |
| Type IV | 20 | 1 (5.0) | 8 (40.0) | 1 (5.0) | 12 (60.0) | 4 (20.0) | 12 (60.0) | 7 (35.0) | 15 (75.0) | 11 (55.0) | 19 (95.0) |
| Type I-IV | 224 | 20 (8.9)* | 65 (29.0) | 12 (5.4)* | 53 (23.7)* | 12 (5.4)* | 52 (23.2)* | 51 (22.8) | 95 (42.4) | 53 (23.7) | 126 (56.3)** |
| WML | 34 | 7 (20.6) | 17 (50.0) | 8 (23.5) | 20 (58.9) | 6 (17.6) | 14 (41.2) | 17 (50.0) | 25 (73.5) | 15 (44.1) | 24 (70.6) |
| Total | 258 | 27 (10.5) | 82 (31.8) | 20 (7.8) | 73 (28.3) | 18 (7.9) | 66 (25.6) | 68 (26.4) | 120 (46.5) | 68 (26.4) | 150 (58.1) |
pro = prospective (blinded) scoring; retro = retrospective (unblinded) scoring; WML = white matter lesion.
*
Significant differences (i.e. P < 0.001) between DIR and other sequences;
**
Significant difference between DIR and other sequences (P < 0.05).