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. 2020 Aug 3;295(43):14565–14577. doi: 10.1074/jbc.RA120.014135

Figure 3.

Figure 3.

Predicted docking poses for modulatory compounds. A, poses for compound docking in a snapshot of rigid-body docking with the AMPAR-γ8 complex (30.18-ns snapshot from 50-ns simulation; γ8 depicted in gray, binding residues as labeled sticks surrounding blue volume of the binding pocket). B, binding poses from induced-fit docking for the three modulatory compounds in the initial structure. In all panels, the binding site is viewed from the AMPAR toward the TARP.