Fig. 2.

Comparison of cell cycle analyses of parental cell line and cisplatin-resistant cells. (A) OVCAR8-CP0, OVCAR8-CP1, and OVCAR8-CP5 cells were treated for 24 h with cisplatin as indicated, stained with propidium iodide, and analyzed by flow cytometry. Cell cycle histograms of one biological replicate of all three cell lines depicting populations of various cell cycle phases is shown. (B) Bar graph displaying the quantitative analysis of distribution of cells in G₀/G₁, S, and G₂ phases of the cell cycle represented as the mean of three biological replicates with the standard error of mean indicated by error bars. n = 3.