Table 2.

Variables Influencing In Vivo Islet Transplantation Outcomes.

Variables	Category	R (AUC_0-28)	P-value	Notes
Viability-semi-automated (%)	Post-isolation assay	−0.299	0.0001	Correlated with good glycemic control
Donor BMI	Donor/Isolation	0.2239	0.0048	Correlated with poor glycemic control
Average islet area (µm2)	Post-isolation assay	0.2204	0.0055	Correlated with poor glycemic control
Post-isolation IPN	Post-isolation assay	−0.2068	0.0094	Correlated with good glycemic control

Pretransplant variables are listed according to the order of statistical relationship to AUC_0-28. Coefficient of correlation (R) is shown instead of coefficient of determination (R ²); negative R value indicates that the factor has a positive correlation with favorable transplantation outcomes (i.e., low AUC_0-28). Only variables with statistically significant correlations with transplantation outcome are listed. An intercorrelation matrix of all variables is shown separately in supplemental Table 2.AUC: area under the curve; BMI: body mass index; IPN: islet particulate number.