Table 2. . CYP2D6 DNA variants that are tested in the present study.
| Variant ID | CYP2D6 Allele | Function | Variant |
|---|---|---|---|
| rs16947 | *2 | Normal (wild type) | 2851C>T (R296C) |
| rs1135840 | *2 | Normal | 4181G>C (S486T) |
| rs35742686 | *3 | None | 2550delA (259 frameshift) |
| rs3892097 | *4 | None | 1847G>A (splicing defect/169 frameshift) |
| Copy number | *5 | Gene deletion/duplication | Gene deletion/duplication |
| rs5030655 | *6 | None | 1708delT (152 frameshift) |
| rs5030656 | *9 | Decreased | 2616delAAG (K281del) |
| rs1065852 | *10 | Decreased | 100C>T (P34S) |
| rs28371706 | *17 | Decreased | 1022C>T (T107I) |
| rs28371725 | *41 | Decreased | 2851C>T (R296C) |