Table 1.
Classification of patients with primary amenorrhea using Tanner staging and Stature
| Clinical features | Tanner stage ≥B3 AND Normal Stature | Tanner stage ≥B3 AND Short Stature | Tanner stage ≤B2 AND Normal Stature | Tanner stage ≤B2 AND Short Stature |
|---|---|---|---|---|
| Hypogonadotropic Hypogonadism (n=117) | 41 (32.8%) | 0 | 71 (60.2%) | 5 |
| XX Gonadal Dysgenesis (n=51) | 14 | 0 | 29 (24.6%) | 8 |
| Turner Syndrome (n=46) | 1 | 2 | 8 | 35 (60.3%) |
| Swyer Syndrome (n=2) | 0 | 0 | 0 | 2 |
| Mullerian agenesis (n=53) | 42 (33.6%) | 8 (80%) | 3 | 0 |
| PCOS (n=13) | 13 | 0 | 0 | 0 |
| CAIS (n=2) | 2 | 0 | 0 | 0 |
| Asherman syndrome (n=4) | 4 | 0 | 0 | 0 |
| Delayed Puberty (n=19) | 4 | 0 | 7 | 8 |
| Hyperprolactinemia (n=4) | 4 | 0 | 0 | 0 |
| Total (n=311a) | 125 | 10 | 118 | 58 |
aExcluding 17 patients who presented with known etiology or exhibited virilization/ambiguous genitalia at presentation suggesting an etiology: Partial AIS (5), Chronic illness (5), CAH (3), DSD (2), Chemotherapy induced PoI (1), Autoimmune PoI (1)