Fig. 2.

Results of integrated cfDNA analysis. The final result of cfDNA analysis integrated from the cfDNA concentration and variants detected in the cfDNA samples of the disease negative (a) and positive (b) groups are shown. A concentration of cfDNA ≥7.0 ng/mL, and/or at least 1 variant detected in plasma samples was used to define a positive cfDNA test. The black solid squares indicate the variants detected in cfDNA samples, and the red solid squares indicate that the result of integrated cfDNA analysis is positive