Table 1:
Baseline characteristics (N = 101) | Patients with histological healing n=56 | Patients without histological healing N=45 |
---|---|---|
Median (IQR) or Percentage (n) | ||
Age at diagnosis of CD (years) | 24 (16–31) | 27 (19–34) |
Gender (male) | 48% (n=27) | 58% (n=26) |
Duration of disease (years) | 14 (9–25) | 9 (3–19) |
Disease phenotype | ||
B1 (inflammatory) | 14% (n=8) | 38% (n=17) |
B2 (stricturing) | 61% (n=34) | 40% (n=18) |
B3 (penetrating) | 25% (n=14) | 22% (n=10) |
Medications at time of colonoscopy: | ||
Oral prednisolone/budesonide | 20% (n=11) | 18% (n=8) |
5-amino-salcylic acid | 9% (n=5) | 11% (n=5) |
6-mercaptopurine/azathioprine | 45% (n=25) | 38% (n=17) |
Methotrexate | 11% (n=6) | 9% (n=4) |
Anti-tumor necrosis factor | 32% (n=18) | 31% (n=14) |
Ustekinumab | 2% (n=1) | 0% (n=0) |
Vedolizumab | 7% (n=4) | 4% (n=2) |
Endoscopic healing | 73% (n=41) | 51% (n=23) |