Table 6.
Multinomial regression for different outcome variables controlled for gestational age, antenatal administration of steroids, mode of delivery, gender, birth weight, multiple birth, IUGR and preeclampsia, and HELLP syndrome.
|
Intracerebral hemorrhage |
Necrotizing enterocolitis§ |
Bronchopulmonary dysplasia |
Retinopathy of prematurity§ |
Periventricular leukomalacia |
Persistent ductus arteriosus§ |
Blood culture positive sepsis |
Death | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | |
| Gestational age | 0.70 (0.67–0.74) | < 0.001 | 0.73 (0.62–0.86) | <0.001 | 0.80 (0.76–0.85) | <0.001 | 0.60 (0.52–0.69) | <0.001 | 0.68 (0.62–0.75) | <0.001 | 0.59 (0.54–0.65) | <0.001 | 0.70 (0.67–0.73) | <0.001 | 0.70 (0.65–0.75) | <0.001 |
| Antenatal steroids | 0.50 (0.42–0.61) | <0.001 | 0.70 (0.35–1.40) | 0.307 | 0.83 (0.65–1.06) | 0.145 | 0.49 (0.31–0.76) | 0.002 | 0.45 (0.32–0.62) | <0.001 | 0.47 (0.35–0.64) | <0.001 | 0.67 (0.55–0.80) | <0.001 | 0.41 (0.31–0.54) | <0.001 |
| Mode of delivery | 1.00 (0.88–1.13) | 0.930 | 0.93 (0.61–1.42) | 0.731 | 1.14 (0.99–1.31) | 0.065 | 1.05 (0.79–1.41) | 0.730 | 1.17 (0.93–1.47) | 0.193 | 1.20 (0.98–1.47) | 0.079 | 1.04 (0.93–1.17) | 0.469 | 1.02 (0.85–1.22) | 0.831 |
| Female Gender | 0.82 (0.73–0.92) | 0.001 | 0.51 (0.34–0.77) | 0.001 | 0.59 (0.52–0.68) | <0.001 | 0.56 (0.41–0.76) | <0.001 | 0.89 (0.71–1.11) | 0.295 | 0.80 (0.65–0.98) | 0.033 | 0.76 (0.68–0.85) | <0.001 | 0.50 (0.41–0.59) | <0.001 |
| Birth weight | 1.00 (1.00–1.00) | <0.001 | 1.00 (1.00–1.00) | 0.086 | 1.00 (1.00–1.00) | <0.001 | 1.00 (1.00–1.00) | <0.001 | 1.00 (1.00–1.00) | 0.244 | 1.00 (1.00–1.00) | <0.001 | 1.00 (1.00–1.00) | <0.001 | 1.00 (1.00–1.00) | <0.001 |
| Multiple birth | 1.06 (0.93–1.20) | 0.402 | 1.22 (0.80–1.85) | 0.351 | 0.97 (0.85–1.12) | 0.693 | 0.93 (0.66–1.30) | 0.675 | 1.12 (0.88–1.42) | 0.354 | 1.06 (0.85–1.32) | 0.620 | 1.03 (0.92–1.16) | 0.594 | 1.57 (1.3–1.89) | <0.001 |
| IUGR | 0.97 (0.80–1.17) | 0.708 | 1.40 (0.77–2.55) | 0.272 | 0.98 (0.82–1.18) | 0.823 | 1.09 (0.68–1.75) | 0.716 | 1.16 (0.81–1.66) | 0.411 | 1.01 (0.73–1.41) | 0.942 | 1.15 (0.98–1.35) | 0.087 | 1.09 (0.84–1.43) | 0.524 |
| Preeclampsia and HELLP | 0.73 (0.60–0.89) | 0.002 | 0.35 (0.15–0.82) | 0.016 | 0.84 (0.70–1.00) | 0.052 | 0.79 (0.50–1.26) | 0.316 | 0.61 (0.40–0.92) | 0.017 | 0.95 (0.69–1.30) | 0.735 | 0.96 (0.82–1.12) | 0.583 | 0.72 (0.55–0.96) | 0.023 |
Reference category for reason of birth was “all other” reasons, as for example clinical chorioamnionitis, preterm labor, pathological cardiotocography, or abruption of placenta.
§
requiring surgery. For better reading, significant values are given in bold.