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. 2020 Jul 2;108(8):3370–3382. doi: 10.1002/jbm.b.34672

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© 2020 The Authors. Journal of Biomedical Materials Research Part B: Applied Biomaterials published by Wiley Periodicals LLC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Post mortem assessment of implant osseointegration by bone histomorphometry: Coloured images show the typical nondecalcified histology examples of (a) metal implant; (b) biphasic calcium phosphate‐coated thermoplastic polyurethane (TPU) implant; and (c) uncoated TPU implant. Note that for (a) and (b) there is bone directly in contact with the implant whereas in C there is a persistent gap between the implant and the surrounding subchondral bone with fibrous encapsulation of the implant. Graph (d): Boxplot showing the histomorphometry analysis of osseointegration of the three different implants using the bone‐implant contact (BIC) percentage. TPU, BCP‐: Thermoplastic polyurethane implants without coating. TPU, BCP++: Thermoplastic polyurethane implants with biphasic calcium phosphate coating. Given values are the average of two observers (intraclass correlation coefficient is .851)