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The extensive hydrogen bond network of the beta‐barrel from a flat hexamer compared to the hydrogen bond network of the screw. (a) The flat hexameric form has a beta‐barrel with an extensive hydrogen bond network. There are several key residues essential for maintaining the overall hexameric architecture. (b) In the screw form, the hydrogen bond network of the beta‐barrel is largely lost, but other key intermolecular interactions near the pore are retained
