Figure 2. Insulin and glucose tolerance tests in adolescent offspring sired by control or obese fathers and sedentary or exercised mothers.

Glucose levels during an intraperitoneal insulin tolerance test (IPITT; A) and glucose (C) and insulin (E) levels during an intraperitoneal glucose tolerance test (IPGTT). Area above (AAC) and under (AUC) the curve for IPITT (B) and IPGTT (D, F), respectively. NS, offspring sired by control‐diet fathers and sedentary mothers (n = 10); HS, offspring sired by obese fathers and sedentary mothers (n = 10); NE, offspring sired by control diet fathers and exercised mothers (n = 9); HE, offspring sired by obese fathers and exercised mothers (n = 10). Values are presented as mean ± SD. *Paternal obesity effect, P < 0.05. #Maternal exercise effect, P < 0.05. +Paternal obesity vs. Maternal exercise interaction, P < 0.05, followed by a least significant difference test (HS vs. HE).