Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Amino acid sequence alignment of BDQ-susceptible frameshift mutations in rv0678. The amino acid sequences of the translated proteins with I16fs and A153fs frameshift mutations (associated with a BDQ-susceptible MIC) were aligned with the Rv0678 wild-type amino acid sequence using ClustalX. In both cases, the two insertion mutations cause the addition of new amino acid residues without altering the frame of the Rv0678 protein and functional residues of the protein.
